SGK1 (d 60 amino acids) (Human) Recombinant Protein
产品名称： SGK1 (d 60 amino acids) (Human) Recombinant Protein
英文名称： SGK1 (d 60 amino acids) (Human) Recombinant Protein
产品编号： P4231
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human SGK1 (NM_005627) N-terminal 60 amino acids deleted partial recombinant protein with GST tag expressed in Sf9 cells.
- Theoretical MW (kDa):
- 73
- Form:
- Liquid
- Preparation Method:
- Insect cell (Sf9) expression system
- Purity:
- ≥ 95% by SDS-PAGE
- Activity:
- 65 nmol phosphate incorporated into Akt/SGK substrate per minute per mg protein at 30°C for 15 minutes using a final concentration of 50 uM ATP (0.83 uCi/assay).
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.25 mM Dithiothreitol, 0.1 mM EGTA, 0.1 mM EDTA, 25% glycerol, 0.1 mM PMSF)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 2 ug/lane SDS-PAGE Stained with Coomassie Blue
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 6446
- Protein Accession#:
- NM_005627
- Gene Name:
- SGK1
- Gene Alias:
- SGK
- Gene Description:
- serum/glucocorticoid regulated kinase 1
- Omim ID:
- 602958
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017247,serine/threonine protein kinase SGK