Anti-HDAC3 Monoclonal Antibody
品牌：solarbio | 货号：K000078M














    

        

            
英文名称
            
Anti-HDAC3 Monoclonal Antibody
        
        

            
宿主
            
Mouse
        
        

            
别名
            
HD3;RPD3;RPD3-2
        
        

            
应用
            
WB
        
        

            
稀释比例
            
WB 1:1000.
        
        

            
交叉反应
            
Human Mouse Rat
        
        

            
蛋白分子量
            
49kDa
        
        

            
Gene ID
            
8841
        
        

            
保存
            
Store at -20°C. Avoid freeze / thaw cycles.
        
        

            
储存液
            
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
        
        

            
纯化方法
            
Affinity purification
        
        

            
亚型
            
IgG1
        
        

            
免疫原
            
Purified recombinant human HDAC3 protein fragments expressed in E.coli.
        
        

            
性状
            
液体
        
        

            
Public Immunogen Range
            
Purified recombinant human HDAC3 protein fragments expressed in E.coli.
        
        

            
Subcellular Locations
            
Cytoplasm Nucleus cytosol
        
        

            
Swiss Prot
            
O15379
        
        

            
克隆号
            
3G3-H6-H10
        
        

            
克隆类型
            
Monoclonal Antibody
        
        

            
背景资料
            
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.