ESR1 (phospho S106) polyclonal antibody-抗体-抗体-生物在线

产品名称： ESR1 (phospho S106) polyclonal antibody

英文名称： ESR1 (phospho S106) polyclonal antibody

产品编号： PAB25290

产品价格： null

产品产地：台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)

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Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding S106 of human ESR1.

Storage Buffer:
In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide)

Recommend Usage:
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
Immunofluorescence (1:100-1:200)
The optimal working dilution should be determined by the end user.

Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Western Blot (Cell lysate)
Western blot analysis of extracts from MCF7 cells using ESR1 (phospho S106) polyclonal antibody (Cat # PAB25290).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ESR1 (phospho S106) polyclonal antibody (Cat # PAB25290).

Gene Summary:
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq