HSD17B8 (Human) Recombinant Protein (Q01)
产品名称： HSD17B8 (Human) Recombinant Protein (Q01)
英文名称： HSD17B8 (Human) Recombinant Protein (Q01)
产品编号： H00007923-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human HSD17B8 partial ORF ( NP_055049, 28 a.a. - 127 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN
- Theoretical MW (kDa):
- 36.74
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 7923
- GeneBank Accession#:
- NM_014234
- Protein Accession#:
- NP_055049
- Gene Name:
- HSD17B8
- Gene Alias:
- D6S2245E,FABG,FABGL,H2-KE6,HKE6,KE6,RING2,SDR30C1,dJ1033B10.9
- Gene Description:
- hydroxysteroid (17-beta) dehydrogenase 8
- Omim ID:
- 601417
- Gene Ontology:
- Hyperlink
- Gene Summary:
- In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq
- Other Designations:
- 17-beta-HSD 8,17-beta-hydroxysteroid dehydrogenase 8,OTTHUMP00000029153,beta-ketoacyl-[acyl-carrier-protein] reductase-like,estradiol 17 beta-dehydrogenase 8,estrogen 17-oxidoreductase,short chain dehydrogenase/reductase family 30C, member 1
- Gene Pathway