CK2 Kinase (Human) Assay/Inhibitor Screening Assay Kit
产品名称： CK2 Kinase (Human) Assay/Inhibitor Screening Assay Kit
英文名称： CK2 Kinase (Human) Assay/Inhibitor Screening Assay Kit
产品编号： KA0071
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
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- Specification
- Product Description:
- CK2 Kinase (Human) Assay/Inhibitor Screening Assay Kit is a single-site, non-quantitative immunoassay for CK2 activity. Plates are pre-coated with a substrate corresponding to recombinant p53, which contains a serine residue that are phosphorylated by CK2 (Casein kinase II). The detector antibody specifically detects only the phosphorylated form of serine46 on p53.
- Reactivity:
- Human
- Storage Instruction:
- Store the kit at 4°C.
- Quality Control Testing:
- Dose dependent curve
Dose dependent curve of recombinant CK2 enzyme reaction.
- Protocol:
Protocol Download
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- Protein kinase CK2 modulates apoptosis induced by resveratrol and epigallocatechin-3-gallate in prostate cancer cells.
Ahmad KA, Harris NH, Johnson AD, Lindvall HC, Wang G, Ahmed K.Mol Cancer Ther. 2007 Mar;6(3):1006-12.
- Application Image
- Functional Study
- Entrez GeneID:
- 1457
- Gene Name:
- CSNK2A1
- Gene Alias:
- CK2A1,CKII
- Gene Description:
- casein kinase 2, alpha 1 polypeptide
- Omim ID:
- 115440
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene. [provided by RefSeq
- Other Designations:
- CK2 catalytic subunit alpha,OTTHUMP00000029925,OTTHUMP00000029926,casein kinase II alpha 1 subunit,casein kinase II alpha subunit,protein kinase CK2
- Gene Pathway