FKBP5 (Human) Recombinant Protein (P01)
产品名称： FKBP5 (Human) Recombinant Protein (P01)
英文名称： FKBP5 (Human) Recombinant Protein (P01)
产品编号： H00002289-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- 所在区域 : 台湾
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- Specification
- Product Description:
- Human FKBP5 full-length ORF ( AAH42605, 1 a.a. - 457 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLPKIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV
- Theoretical MW (kDa):
- 76.01
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Publication Reference
- 1.
- Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent.
Horibe T, Kohno M, Haramoto M, Ohara K, Kawakami K.J Transl Med. 2011 Jan 14;9:8.
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2289
- GeneBank Accession#:
- BC042605
- Protein Accession#:
- AAH42605
- Gene Name:
- FKBP5
- Gene Alias:
- FKBP51,FKBP54,MGC111006,P54,PPIase,Ptg-10
- Gene Description:
- FK506 binding protein 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq
- Other Designations:
- 51 kDa FK506-binding protein 5,54 kDa progesterone receptor-associated immunophilin,FF1 antigen,FK506-binding protein 5,HSP90-binding immunophilin,OTTHUMP00000016268,T-cell FK506-binding protein,peptidylprolyl cis-trans isomerase,rotamase
- Related Disease
- Addison Disease
- Alcoholism
- Anxiety Disorders
- Asthma
- Asthma
- Bipolar Disorder
- Depressive Disorder
- Depressive Disorder, Major
- Dysthymic Disorder
- Genetic Predisposition to Disease
- Glaucoma, Open-Angle
- HIV Infections
- Inflammation
- Mood Disorders
- Personality Inventory
- Personality Tests
- Recurrence
- Stress Disorders, Post-Traumatic
- Stress, Psychological