NQO1 polyclonal antibody
产品名称： NQO1 polyclonal antibody
英文名称： NQO1 polyclonal antibody
产品编号： PAB6134
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of NQO1.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human NQO1.
- Sequence:
- C-SIPTDNQIKARK
- Host:
- Goat
- Theoretical MW (kDa):
- 30.9, 27.3, 26.4
- Reactivity:
- Dog, Human, Mouse
- Specificity:
- This products is expected to recognize all three reported isoforms (NP_000894.1, NP_001020604.1 and NP_001020605.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.03-0.1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- NQO1 stabilizes p53 through a distinct pathway.
Asher G, Lotem J, Kama R, Sachs L, Shaul Y.Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3099-104. Epub 2002 Feb 26.
- Entrez GeneID:
- 1728
- Protein Accession#:
- NP_000894.1;NP_001020604.1;NP_001020605.1
- Gene Name:
- NQO1
- Gene Alias:
- DHQU,DIA4,DTD,NMOR1,NMORI,QR1
- Gene Description:
- NAD(P)H dehydrogenase, quinone 1
- Omim ID:
- 125860
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- DT-diaphorase,NAD(P)H menadione oxidoreductase 1, dioxin-inducible,NAD(P)H:Quinone acceptor oxidoreductase type 1,NAD(P)H:menadione oxidoreductase 1,NAD(P)H:quinone oxireductase,azoreductase,diaphorase (NADH/NADPH) (cytochrome b-5 reductase),diaphorase-4,
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