IRF1 monoclonal antibody (M01), clone 2E4
产品名称： IRF1 monoclonal antibody (M01), clone 2E4
英文名称： IRF1 monoclonal antibody (M01), clone 2E4
产品编号： H00003659-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant IRF1.
- Immunogen:
- IRF1 (NP_002189, 216 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- PMPSTSEATTDEDEEGKLPEDIMKLLEQSEWQPTNVDGKGYLLNEPGVQPTSVYGDFSCKEEPEIDSPGGDIGLSLQRVFTDLKNMDATWLDSLLTPVRLPSIQAIPCAP
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Defining critical roles for NF-?eB p65 and type I interferon in innate immunity to rhinovirus.
Bartlett NW, Slater L, Glanville N, Haas JJ, Caramori G, Casolari P, Clarke DL, Message SD, Aniscenko J, Kebadze T, Zhu J, Mallia P, Mizgerd JP, Belvisi M, Papi A, Kotenko SV, Johnston SL, Edwards MR.EMBO Mol Med. 2012 Dec;4(12):1244-60. doi: 10.1002/emmm.201201650. Epub 2012 Nov 14.
- Applications
- Western Blot (Cell lysate)
- IRF1 monoclonal antibody (M01), clone 2E4 Western Blot analysis of IRF1 expression in COLO 320 HSR ( Cat # L020V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged IRF1 is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 3659
- GeneBank Accession#:
- NM_002198
- Protein Accession#:
- NP_002189
- Gene Name:
- IRF1
- Gene Alias:
- IRF-1,MAR
- Gene Description:
- interferon regulatory factor 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq
- Other Designations:
- interferon regulatory factor-1
- Related Disease
- Acute Disease
- Arthritis, Juvenile Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Breast cancer
- Breast Neoplasms
- Bronchial Hyperreactivity
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Celiac Disease
- Crohn Disease
- Crohn's disease
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Graves Disease
- Hepatitis B