PPP2R2B monoclonal antibody (M02), clone 1F3
产品名称： PPP2R2B monoclonal antibody (M02), clone 1F3
英文名称： PPP2R2B monoclonal antibody (M02), clone 1F3
产品编号： H00005521-M02
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant PPP2R2B.
- Immunogen:
- PPP2R2B (AAH31790.1, 22 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- TEADIISTVEFNHTGELLATGDKGGRVVIFQREQESKNQVHRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQQNAAYFLLSTNDKTVKLWKVSERDKRPE
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.4 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunoprecipitation
- Immunoprecipitation of PPP2R2B transfected lysate using anti-PPP2R2B monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with PPP2R2B MaxPab rabbit polyclonal antibody.
- Protocol Download
- Entrez GeneID:
- 5521
- GeneBank Accession#:
- BC031790
- Protein Accession#:
- AAH31790.1
- Gene Name:
- PPP2R2B
- Gene Alias:
- B55-BETA,FLJ95686,MGC24888,PP2A-B55BETA,PP2A-PR55B,PP2AB-BETA,PP2APR55-BETA,PR2AB-BETA,PR2AB55-BETA,PR2APR55-BETA,PR52B,PR55-BETA,SCA12
- Gene Description:
- protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 66-78 copies in cases of SCA12. [provided by RefSeq
- Other Designations:
- PP2A, subunit B, B-beta isoform,PP2A, subunit B, R2-beta isoform,beta isoform of regulatory subunit B55, protein phosphatase 2,protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform,serine/threonine protein phosphatase 2A, 55 kDa
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Cerebellar Ataxia
- Chronic Disease
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Essential Tremor
- Essential tremor
- Genetic Predisposition to Disease
- Genomic Instability
- Parkinson disease
- Schizophrenia
- Schizophrenia
- Spinocerebellar ataxia
- Spinocerebellar Ataxias
- Tobacco Use Disorder