CD81 monoclonal antibody, clone M38
产品名称： CD81 monoclonal antibody, clone M38
英文名称： CD81 monoclonal antibody, clone M38
产品编号： MAB6435
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD81.
- Immunogen:
- Native purified CD81 from human T-ALL cell line (MOLT-4).
- Host:
- Mouse
- Theoretical MW (kDa):
- 25
- Reactivity:
- Cat, Human, Rabbit
- Specificity:
- This antibody reacts with CD81, a 25 KDa member of the tetraspanin family, expressed on majority of cells.
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4 (15 mM sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes.
Escola JM, Kleijmeer MJ, Stoorvogel W, Griffith JM, Yoshie O, Geuze HJ.J Biol Chem. 1998 Aug 7;273(32):20121-7.
- 2.
- Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82.
Imai T, Kakizaki M, Nishimura M, Yoshie O.J Immunol. 1995 Aug 1;155(3):1229-39.
- 3.
- C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and associate with each other and with CD4 or CD8 in T cells.
Imai T, Yoshie O.J Immunol. 1993 Dec 1;151(11):6470-81.
- Application Image
- Western Blot
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunocytochemistry
- Immunoprecipitation
- Functional Study
- Flow Cytometry
- Entrez GeneID:
- 975
- Gene Name:
- CD81
- Gene Alias:
- S5.7,TAPA1,TSPAN28
- Gene Description:
- CD81 molecule
- Omim ID:
- 186845
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. [provided by RefSeq
- Other Designations:
- 26 kDa cell surface protein TAPA-1,CD81 antigen,CD81 antigen (target of antiproliferative antibody 1),target of antiproliferative antibody 1
- Gene Pathway
- Related Disease
- Atherosclerosis
- Carcinoma, Hepatocellular
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Kidney Failure, Chronic
- Liver Neoplasms
- Lung Neoplasms
- Lymphoproliferative Disorders
- Multiple Myeloma
- Obesity
- Occupational Diseases
- Pulmonary Disease, Chronic Obstructive
- Urinary Bladder Neoplasms
- Waldenstrom Macroglobulinemia
- Werner syndrome